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Image Search Results
Journal: Science Advances
Article Title: A dominant function of LynB kinase in preventing autoimmunity
doi: 10.1126/sciadv.abj5227
Figure Lengend Snippet: Serum was collected from 8.5-month-old male and female mice and assayed for antibody production. ( A ) Serum ANA detection via FITC staining of Hep-2 cells. Occurrence of splenomegaly or low body mass in the same individual is indicated (+ yes, − no). ( B ) Frequency of ANA negativity (−) and positivity (+). Occurrence of splenomegaly or low body mass in the same individual (+ yes, − no) as defined in . Significance for raw contingency data was assessed via two-sided Fisher’s exact test with Bonferroni correction for multiple comparisons. Analysis pool: WT 4 M + 8 F, LynA KO 6 M + 6 F, LynB KO 4 M + 8 F, and Lyn KO 6 M + 6 F. ( C ) ELISA-derived IgM levels and associated splenomegaly or low body mass; error bars, SEM.
Article Snippet: Kallestad
Techniques: Staining, Enzyme-linked Immunosorbent Assay, Derivative Assay